![]() Serine + PA - phosphatidylserine (PS) Ethanolamine + PA - phosphatidylethanolamine (cephalin) Choline + PA - phosphatidylcholine (lecithin) PC Inositol + PA - phosphatidylinositol (PI) Glycerol + PA phosphatidylglycerol (PG) functions in the body, for example, 1-as components of lung surfactant and 2-essential components of bile, where their البايل هي المكان الذي له وظائف تنظيف detergent properties aid "in the solubilization of cholesterol.Membrane phospholipids also function as : 1- a reservoir حافظ for intracellular messengers, and, 2-for some proteins, phospholipids serve as anchors مرساه ( مثبت ) to cell membranes. The hydrohilic polar head extends outward, facing intracellular or extracellular aqueous environment (see Figure).In membranes, the hydrophobic portion is associated with the nonpolar portions such as glycolipids, proteins, and cholesterol.Amphipathicمتردد ( محب وكاره للماء )in nature, has a hydrophilic head (phosphate + alcohol eg., serine, ethanolamine, and choline) and a long, hydrophobic tail (fatty acids or derivatives ).Polar compounds composed of alcohol attached by a مربوط بـرابطهphosphodiesterbridge to either diacylglycerol or sphingosine.Role of phsophatidylinositol in signal transduction and membrane anchoring. Role of phosphatidyl choline in lung surfactant 6. Degradation of phospholipids by phosphalipases. ![]() Synthesis of phospholipids: Phosphatidic acid, phosphatidyl-choline, ethanolamine and serine, cardiolipin and sphingomyelin etc. Structure of Glycerophospholipids and sphingolipids. To study the role of phospholipids like phosphatidylinositol in signal transduction and membrane anchoring choline, ethanolamine and serine, cardiolipin and sphingomyelin etc. To discuss the synthesis of phospholipids of clinical and physiological relevance and their degradation by phospholipases. To study the structure of physiologically important phospholipid classes- glycerophospholipids and sphingolipids.
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